Elefteria PsillakisAntonio CanalsKonstantina TyrovolaAnna MastromichaliIván P Román2024-10-312024-10-3120142015-09-25I. P Román, A. Mastromichali, K. Tyrovola, A. Canals, E. Psillakis , "Rapid determination of octanol–water partition coefficient using vortex-assisted liquid–liquid microextraction ",J. of Chromat.,vol.1330, pp. 1–5,2014,doi:10.1016/j.chroma.2014.01.003https://dspace.library.tuc.gr/handle/123456789/1017Abstract Vortex-assisted liquid–liquid microextraction (VALLME) coupled with high- performance liquid chromatography (HPLC) is proposed here for the rapid determination of octanol–water partitioning coefficients (K ow). VALLME uses vortex agitation, a mild emulsification procedure, to disperse microvolumes of octanol in the aqueous phase thus increasing the interfacial contact area and ensuring faster partitioning rates. With VALLME, 2 min were enough to achieve equilibrium conditions between the octanolic and aqueous .4pagesenhttp://creativecommons.org/licenses/by/4.0/EXPERIMENTALPeer-Reviewed Journal Publication